Yes, because Brexit, the dynamics of a number of the significant pairs have changed. Just be certain that the GB/USD and GB/JPY are consistent together, if they're not, then stay with the one that has the important Trend. Look out for information for Pound Pairs. I do all of my transactions manually, you may miss out on some moves but Automation will reduce you pips in the end.
You just have to Learn How to trade manually following the GBP pairs on the Hour four Time Frames. They're still the leaders to the Core5 Basket Pairs. Gbp/JPy and GBP/Usd would be the pairs to follow. You must have Support and Resistance lines on those pairs and exchange the basket together with those traces.
If I'm in deep draw down, I double my lot dimensions and trade my way out of the Draw down, maybe not recommended rather than what I do frequently but will help me get out of the draw down fast and into gain. You have to be able to Interpret what you see. There's a good deal of pullbacks from any significant move on Core5. Backs.
It may take a couple of days. The Market has changed and so we traders will need to set up new rules of engagement to attack. It's not quite as simple as it used to before Brexit I have to say.
There's a whole lot more of sitting ones hand nowadays too. If in doubt, stay out!!
Only a thought and the best.